منابع مشابه
Statins, immunomodulation, and infections: a complex and unresolved relationship.
Statins are now among the most widely used drugs in the world. They have proven efficacy in treating hyperlipidemia and in the prevention of vascular disease, with randomized data showing that they confer benefits in terms of clinical outcomes, including mortality. However, no drugs are without their adverse effects. The most well-known adverse effect of statins is probably muscle toxicity, whi...
متن کاملImmunomodulation by fungal toxins.
The availability of immunotoxicity data for fungal toxins varies considerably for different toxins. The following is a comprehensive review of the most recent literature on the immunotoxicity of aflatoxins, fumonisins, gliotoxin, ochratoxins, patulin, and trichothecenes. Aflatoxin is an immunomodulating agent that acts primarily on cell-mediated immunity and phagocytic cell function. In additio...
متن کاملImmunomodulation by Mesenchymal Stem Cells
Mesenchymal stem cells (MSCs) are pluripotent stromal cells that have the potential to give rise to cells of diverse lineages. Interestingly, MSCs can be found in virtually all postnatal tissues. The main criteria currently used to characterize and identify these cells are the capacity for self-renewal and differentiation into tissues of mesodermal origin, combined with a lack in expression of ...
متن کاملImmunomodulation by thalidomide and thalidomide analogues.
Tumour necrosis factor á (TNFá), a key cytokine involved in the host immune response, also contributes to the pathogenesis of both infectious and autoimmune diseases. To ameliorate the pathology resulting from TNFá in these clinical settings, strategies for the inhibition of this cytokine have been developed. Our previous work has shown that the drug thalidomide is a partial inhibitor of TNFá p...
متن کاملImmunomodulation of Autoimmune Arthritis by Herbal CAM
Rheumatoid arthritis (RA) is a debilitating autoimmune disease of global prevalence. The disease is characterized by synovial inflammation leading to cartilage and bone damage. Most of the conventional drugs used for the treatment of RA have severe adverse reactions and are quite expensive. Over the years, increasing proportion of patients with RA and other immune disorders are resorting to com...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Arthritis Research & Therapy
سال: 2000
ISSN: 1478-6362
DOI: 10.1186/ar-2000-66870